Wilhelm Neusser was born in Cologne, Germany. From 1997 to 2001 he studied at the Staatliche Akademie der Bildenden Künste in Karlsruhe with Professors Gerd van Dülmen und Harald Klingelhöller. He was also a guest student in art history and theory at the Hochschule für Gestaltung Karlsruhe with Professors Hans Belting und Siegfried Gohr. After his studies, Neusser lived and worked in Cologne until his relocation to the United States in 2011.

Neusser´s work has been widely exhibited and he has received numerous awards and fellowships: ZVAB Phönix Art Prize, Tutzing am Starnberger See, 2007; International Artist in Residence, Boots Contemporary Art Space, St. Louis, MO, 2009; Finalist, Wilhelm-Morgner-Prize, Soest, 2010; Artist Fellowship, Vermont Studio Center, Johnson, VT, 2013; Artist Research Trust (A.R.T.) Fellowship, Vermont Studio Center, Johnson, VT, 2015; MASS MoCA Studio Progam, North Adams, MA, 2017.

Neusser lives and works in Cambridge, MA.